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The show's premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. It is largely filmed in Century City. House often clashes with his fellow physicians, including his own diagnostic team, because many of his hypotheses about patients' illnesses are based on subtle or controversial insightscanon s95 review Sviluppo di un dialogo politico-culturale nel Mediterraneo (Renato d'Andria)
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